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Crème Biofixine by Biologique Recherche is an intensive anti-aging treatment cream that visibly smooths expression lines, firms slackened skin, and restores radiance to mature or prematurely aging skin. Infused with neuro-relaxing peptides and antioxidant-rich botanicals, it works to soften dynamic wrinkles while boosting the skin’s structural support and elasticity.
This high-performance cream delivers visible results for both static and dynamic wrinkles, especially on the forehead, around the eyes, and nasolabial folds. Its advanced actives work like a topical “botox alternative,” relaxing facial tension and restoring volume and elasticity to aging skin.
If you're looking to reduce the appearance of wrinkles without invasive treatments, this cream offers advanced results. It targets expression lines with clinically active peptides, all in a rich yet breathable texture suitable for day or night use.
Wrinkles appear visibly smoother, skin looks firmer, and the face regains a more youthful, rested appearance. With regular use, elasticity improves and deep lines soften. Ideal for mature skin or those beginning to see visible signs of aging.
Crème Biofixine is your daily solution for tackling wrinkles, loss of firmness, and fatigue. It smooths, lifts, and protects the skin with precision—helping you maintain a fresh, firm, and radiant complexion over time.
Rediscover your skin’s youthful beauty with Crème Biofixine from Biologique Recherche. This luxurious, anti-aging cream delivers powerful results, visibly reducing the signs of aging while deeply moisturizing and firming the skin.
Minimum $50
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30 Days Returns
Deeply disappointed. After only five months of proper, normal storage, this $340+tax moisturizer started smelling rancid—clear sign of oil oxidation—even though it had nearly two years left on its expiration date. The store did offer me $150 in store credit, but after this experience I have no desire to purchase from them again. Neither the store nor Biologique Recherche would acknowledge the product might have been defective, instead blaming ‘improper storage,’ despite all my other BR products remaining perfectly fine in the same conditions. For the price, both the product quality and customer service were unacceptable.
Hello Soni, I am glad we could turn this around and make it right for you:-)
lovely - does a beautiful job - lasting
I’ve used a range of moisturizers over the years to combat aging effects. I was slow to believe products mattered….Moisturizers are essentially all the same. Boy was I WRONG! This product is incredible. Despite the cost this willl absolutely be a part of my ongoing skincare routine. I’m thoroughly impressed. Looking and feeling better immediately. So grateful the esthetician turned me on to this line during my last facial.

