Biologique Recherche Lotion P50 is the exfoliating toner that Aida Bicaj has relied on — and introduced to her clients — for nearly three decades. Formulated to purify, rebalance, and strengthen the skin, it dissolves dead cell buildup, restores pH equilibrium, and prepares the complexion to absorb what follows. This is the modern formulation developed after the original phenol-based Lotion P50 1970 was discontinued, delivering the same results with a safer, more compatible profile.
Not sure which P50 is right for your skin? See the guide in the first tab below.
The original formula. Best for skin that is oily, congested, or prone to keratinization. Regulates sebum, refines texture, and maintains clarity. Also effective for treating ingrown hairs.
Key actives: Lactic Acid, Salicylic Acid, Niacinamide, Sulfur, Magnesium Chloride
A more conditioning version of the original. Best for skin that lacks tone or vitality but is not overly sensitive. Fortifies and stimulates epidermal functions while gently exfoliating.
Key actives: Walnut extract, Yeast extract, Plankton, Brewer's yeast
The gentlest formulation. Best for thin, reactive, or easily irritated skin. Balances exfoliating acids with soothing ingredients to purify without provoking a response.
Key actives: Arnica, Lactic Acid, Salicylic Acid, Glycerin, Arctium Lappa root
Formulated specifically for dull skin with dark spots or uneven pigmentation. Inhibits melanin synthesis, brightens the complexion, and prepares skin for the full PIGM 400 protocol.
Key actives: Wasabi extract, Flavonoids, Vitamin B3
The body-specific formulation. Purifies, rebalances pH, and accelerates cellular renewal on skin below the neck. A natural extension of the P50 facial routine.
Still unsure? Our estheticians are available for consultations at both our Upper East Side and Tribeca locations.
Lotion P50 exfoliates, rebalances, and conditions the skin's surface with daily use. Over time it refines texture, clarifies tone, and builds epidermal resilience.
Use morning and/or evening. If new to exfoliating acids, begin every other day and increase to daily use as your skin adjusts.
Full INCI: Water (Aqua), Gluconolactone, Lactic Acid, Glycerin, Propylene Glycol, Niacinamide, Citric Acid, Ethoxydiglycol, Magnesium Chloride, Cochlearia Armoracia (Horseradish) Root Extract, Arctium Lappa Root Extract, Rumex Acetosa Leaf Extract, Allium Cepa (Onion) Bulb Extract, Commiphora Myrrha Resin Extract, Phytic Acid, Salicylic Acid, Thymus Vulgaris (Thyme) Flower/Leaf Oil, Vinegar (Acetum), Sorbitol, Sodium Benzoate, Phenoxyethanol, Potassium Sorbate, Sodium Bisulfite.
In the first weeks, skin feels cleaner and smoother. With continued use, pores appear more refined, tone becomes more even, and the complexion takes on the clarity associated with a consistent Biologique Recherche routine. Lotion P50 does not deliver quick fixes — it delivers measurable improvement over time, which is why it has remained central to Aida's protocols since she first brought it to her Upper East Side clients in the 1990s.
Consistent use reveals smoother texture, minimized pores, and a clearer, brighter complexion. Lotion P50 remains a cornerstone for balanced, healthy skin—offering the trusted results of the original formula, now with a safer, more universally compatible profile.


