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The Biologique Recherche Guide

Biologique Recherche
Pigmentation Routine

Formulas for skin that looks dull or uneven. The PIGM 400 routine targets dark spots and helps unify the complexion, step by step.

A routine to unify the complexion

The PIGM 400 range targets dark spots and uneven tone. Biologique Recherche builds the routine in three steps: a Lotion P50 to refine the epidermis, a targeted serum for clarity and radiance, and a cream for uneven skin. Used together and consistently, they support a more even, luminous-looking complexion over time.

Discover the Biologique Recherche method

How it works

The routine

Follow these steps in order, morning and evening.

Cleanse

Lait Dermo-S soothes, moisturizes and removes make-up. Massage over dry face, neck and décolleté, then rinse with cool water or remove with a damp cloth.

LAIT DERMO-S

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Refine with Lotion P50 PIGM 400

Exfoliates, purifies and targets dark spots. Press gently into the face, neck and décolleté with a cotton pad. If you are new to exfoliating lotions, start every other day.

Lotion P50 PIGM 400

Treat with Sérum PIGM 400

Targets dark spots and brightens for a more even tone. Apply over the whole face or focus on uneven areas. Biologique Recherche also includes Sérum A-Glyca in this routine for skin that shows signs of aging.

Serum PIGM 400 · Serum A-Glyca

Protect with Crème PIGM 400

Targets dark spots, brightens and protects. Massage over the face, neck and décolleté with upward strokes to finish the routine.

Creme PIGM 400

Boost and finish

Masque PIGM 400 is a sheet mask that brightens and perfects, for a weekly boost or before an event. BioKiss protects and replenishes the lips and other dry, delicate areas.

Masque PIGM 400 · BioKiss - Soothing and moisturizing balm

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The products

Soothing & Calming Cleanser

LAIT DERMO-S

Lait Dermo-S: Ultra-Gentle Cleansing Milk for Reactive and Sensitive Skin Lait Dermo-S by Biologique Recherche is a calming, lipid-rich cleansing milk formulated specifically for fragile, reactive, or intolerant skin. It gently removes...

Exfoliating & Brightening Lotion

Lotion P50 PIGM 400

For dull skin with uneven pigmentation. Exfoliates and brightens. Biologique Recherche recommends it for first-time P50 users.

Key actives: lactic, mandelic and salicylic acids, niacinamide, vitamin C

How to use: After your Lait, dab over face, neck and décolleté with a cotton pad in upward strokes. Don't scrub. In week one, dampen the pad with water first. Avoid the eye area.

Brightening & Evening Serum

Serum PIGM 400

Sérum PIGM 400: Targeted Brightening Serum for Dark Spots and Uneven Tone Sérum PIGM 400 by Biologique Recherche is a powerful brightening treatment designed to reduce hyperpigmentation and enhance skin radiance. Packed...

Anti-aging & Anti-glycation Serum

Serum A-Glyca

Sérum A-Glyca: Anti-Glycation Serum for Firmer, More Radiant Skin Sérum A-Glyca by Biologique Recherche is a targeted anti-aging treatment that defends skin against glycation—a key factor in collagen degradation and premature aging....

Moisturizing & Redensifying Treatment

Creme PIGM 400

Crème PIGM 400: Brightening Cream for Dark Spots and Uneven Skin Tone Crème PIGM 400 by Biologique Recherche is a powerful brightening moisturizer formulated to reduce the appearance of pigmentation, unify the...

Brightening & Illuminating Treatment

Masque PIGM 400

Masque PIGM 400: Illuminating Sheet Mask for Uneven Skin Tone Reveal a brighter, more even complexion with Masque PIGM 400, a powerful brightening sheet mask from Biologique Recherche. Designed to combat dullness,...

Questions

Good to know

How long before I see a more even tone?

Pigmentation fades gradually, so consistency matters more than intensity. Use the routine daily and give it several weeks before judging results.

Do I need sun protection?

Yes. Sun exposure is one of the main triggers of dark spots, so daily sun protection helps protect the results of your PIGM 400 routine.

What about dark areas on the body?

Cible PIGM 400 is a roll-on made for localized dark areas on the body, such as the knees, elbows and underarms. The face routine above is for the face, neck and décolleté.

Is this routine right for my skin?

Pigmentation has many causes, and the right protocol depends on your Skin Instant®. Our estheticians can assess your skin at our Upper East Side and Tribeca locations.

A more even, luminous complexion.

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