Sérum Vivant by Biologique Recherche is the brand's advanced answer to a skin concern that rarely resolves on its own: adult, persistent blemishes. Born from the cult legacy of the Vivant collection, this multi-corrective serum was developed for skin that keeps breaking out past its twenties—skin that needs more than aggressive drying to find balance. Formulated with a biotechnological blend of prebiotics, postbiotics, and biomimetic actives, it targets blemishes and redness while preserving the skin's barrier, hydration, and comfort.
Sérum Vivant targets persistent imperfections without compromising the skin barrier. It reduces the appearance of blemishes and redness while supporting hydration and microbiome balance—so skin clears without becoming reactive, tight, or dehydrated.
It's not another drying spot treatment—it's a rebalancing ritual for adult, blemish-prone skin. Whether your skin is reactive, dehydrated, or stuck in a cycle of recurring breakouts, Sérum Vivant delivers visibly clearer, calmer skin without sacrificing comfort.
When layering with other Biologique Recherche serums as part of a persistent blemish protocol, apply Sérum Vivant just before Spectral, as the second-to-last serum in your routine.
Cold-process formulated to protect the integrity of its yeast-derived actives, Sérum Vivant is a gelled aqueous serum with a slightly viscous flow, a lightweight, silky glide, and a soft, non-greasy finish.
Tested on blemish-prone skin, including sensitive skin, under dermatological control (21 volunteers, twice-daily application over 28 days).
What is Sérum Vivant for?
A multi-corrective serum for adult, blemish-prone skin—specifically persistent, recurring blemishes that tend to show up after age 25. It reduces the appearance of blemishes and redness while supporting microbiome balance, barrier function, and hydration.
How is it different from Masque Vivant?
Masque Vivant is the cult-favorite mask from the same Vivant collection. Sérum Vivant extends that legacy into a daily leave-on serum, built on the same biotechnological, yeast-derived actives, for targeted day-to-day correction.
Is it suitable for sensitive skin?
Yes. It was tested on blemish-prone skin, including sensitive skin, under dermatological control, and is formulated to reduce imperfections while preserving skin comfort and barrier integrity.
How often should I use it?
Twice daily—morning and evening—following cleansing and toning, and before your treatment cream.
Clinically shown to reduce persistent blemishes by 42% after 28 days.
Cuts excess sebum by 27% in 14 days — without over-drying skin.
Reduces water loss and supports the microbiome, so skin stays calm and comfortable.
Helps support the skin microbiome and contributes to the proper functioning of the skin barrier and to overall skin comfort.
Helps target blemish-related redness and supports the balance of blemish-prone skin.
A gentle, biotech blemish-targeting ingredient.









